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Intestinal cell damage and systemic immune activation in individuals reporting sensitivity to wheat in the absence of coeliac disease
NEW YORK, NY (July 26, 2016)—A new study may explain why people who do not have celiac disease or wheat allergy nevertheless experience a variety of gastrointestinal and extra-intestinal symptoms after ingesting wheat and related cereals.
*The findings suggest that these individuals have a weakened intestinal barrier, which leads to a body-wide inflammatory immune response.
Findings from the study, which was led by researchers from Columbia University Medical Center (CUMC), were reported in the journal Gut.
*The findings suggest that these individuals have a weakened intestinal barrier, which leads to a body-wide inflammatory immune response.
Findings from the study, which was led by researchers from Columbia University Medical Center (CUMC), were reported in the journal Gut.
Dr. Alaedini added, “The data suggest that, in the future, we may be able to use a combination of biomarkers to identify patients with non-celiac wheat sensitivity, and to monitor their response to treatment.”
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The study is titled, “Intestinal cell damage and systemic immune activation in individuals reporting sensitivity to wheat in the absence of celiac disease.”
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The study is titled, “Intestinal cell damage and systemic immune activation in individuals reporting sensitivity to wheat in the absence of celiac disease.”
read more...
Sources :
http://newsroom.cumc.columbia.edu/blog/2016/07/26/columbia-researchers-find-biological-explanation-wheat-sensitivity-2/
http://gut.bmj.com/content/early/2016/07/21/gutjnl-2016-311964
http://newsroom.cumc.columbia.edu/blog/2016/07/26/columbia-researchers-find-biological-explanation-wheat-sensitivity-2/
http://gut.bmj.com/content/early/2016/07/21/gutjnl-2016-311964
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